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The integrated phenotype

Courtney J Murren1

  • 1Department of Biology, College of Charleston, 66 George Street, Charleston, SC 29424, USA. murrenc@cofc.edu

Integrative and Comparative Biology
|May 18, 2012
PubMed

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Although Mendel chose seven unrelated traits in peas to study gene segregation, most traits involve multiple gene interactions that create a spectrum of phenotypes. When the interaction of various genes or alleles at different locations influences a phenotype, this is called epistasis. Epistasis often involves one gene masking or interfering with the expression of another (antagonistic epistasis). Epistasis often occurs when different genes are part of the same biochemical pathway. The...