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Related Concept Videos

Radiological Investigation II: MRI and Ventilation Perfusion Scan01:30

Radiological Investigation II: MRI and Ventilation Perfusion Scan

Description
Magnetic Resonance Imaging (MRI) and Ventilation Perfusion Scans are two radiological investigations that offer detailed diagnostic images of the body, particularly lung structures.
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Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
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A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
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Understanding and evaluating diffusion and perfusion is critical in assessing a patient's respiratory and circulatory health. These processes play key roles in maintaining the body's internal environment, ensuring that tissues receive adequate oxygen while waste products are efficiently removed.
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Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...
Imaging Studies II: Positron Emission Tomography and Scintigraphy01:25

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Positron Emission Tomography (PET) is a medical imaging technique that provides crucial insights into the body's physiological functions at a molecular level. It is an indispensable resource for diagnosing, staging, and monitoring various illnesses, notably cancer, neurological disorders, and cardiovascular conditions.
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Updated: May 22, 2026

Phase-Resolved Functional Lung MRI for Pulmonary Ventilation and Perfusion (V/Q) Assessment
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Imaging lung perfusion.

Susan R Hopkins1, Mark O Wielpütz, Hans-Ulrich Kauczor

  • 1Departments of Medicine and Radiology, Pulmonary Imaging Laboratory, University of California-San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA. shopkins@ucsd.edu

Journal of Applied Physiology (Bethesda, Md. : 1985)
|May 19, 2012
PubMed
Summary
This summary is machine-generated.

Modern imaging techniques like MRI, CT, PET, and SPECT offer advanced ways to study pulmonary blood flow, each with unique strengths and limitations for physiological research.

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Area of Science:

  • Physiology
  • Medical Imaging

Background:

  • Early studies in 1961 used radioactive tracers to describe gravitational differences in pulmonary blood flow.
  • Significant advancements in imaging technology have occurred since initial measurements.

Purpose of the Study:

  • To provide an overview of commonly used pulmonary blood flow imaging techniques.
  • To discuss the unique issues and considerations associated with each technique for physiological experiments.

Main Methods:

  • Review of modern imaging modalities including Magnetic Resonance Imaging (MRI), Computerized Tomography (CT), Positron Emission Tomography (PET), and Single Photon Emission Computed Tomography (SPECT).

Main Results:

  • Techniques vary in resolution, contrast agents/tags, and radiation exposure.
  • Different methods measure varying aspects of blood flow, from capillary perfusion (PET, SPECT) to larger vessels (MRI, CT).

Conclusions:

  • The choice of imaging technique impacts data quantification, interpretation, and experimental design.
  • Understanding technique-specific characteristics is crucial for effective pulmonary blood flow research.