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Updated: May 22, 2026
06:38
A Syngeneic Mouse Model of Metastatic Renal Cell Carcinoma for Quantitative and Longitudinal Assessment of Preclinical Therapies
Published on: April 12, 2017
Synchronous renal malignancy presenting as recurrent urinary tract infections
1Department of Internal Medicine, Lutheran Medical Center, Brooklyn, NY 11220, USA.
Case Reports in Urology
|May 19, 2012
Summary
Simultaneous renal cell carcinoma (RCC) and upper tract urothelial carcinoma are rare. This case highlights the importance of preoperative evaluation for synchronous malignancies in the same kidney, especially when considering nephron-sparing surgery.
Area of Science:
- Urology
- Oncology
- Pathology
Background:
- Renal cell carcinoma (RCC) and upper tract urothelial carcinoma (UTUC) are common urological malignancies.
- Simultaneous occurrence of these two distinct malignancies within the same kidney is exceptionally rare.
Observation:
- A patient presented with suspected RCC, necessitating unilateral nephrectomy.
- Preoperative imaging indicated renal pelvic involvement, confirmed by cystoscopy and biopsy.
- The confirmed lesion was transitional cell carcinoma of the superior pelvis, a type of UTUC.
Findings:
- The patient had synchronous renal cell carcinoma and transitional cell carcinoma in the same kidney.
- Preoperative diagnosis of both malignancies was crucial for treatment planning.
Implications:
- This case underscores the importance of thorough preoperative assessment for synchronous tumors in urological malignancies.
- Accurate preoperative diagnosis facilitates appropriate surgical planning, including nephron-sparing approaches when feasible.
- Highlights the diagnostic challenges and management considerations for rare co-occurring kidney cancers.
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