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Ookluc: A Plasmodium berghei Line for Identifying Transmission-blocking Compounds
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Choline analogues in malaria chemotherapy.

Suzanne Peyrottes1, Sergio Caldarelli, Sharon Wein

  • 1Institut des Biomolécules Max Mousseron, UMR 5247 CNRS-UM1-UM2, Université Montpellier 2, place E. Bataillon, 34095 Montpellier, France. peyrottes@univ-montp2.fr

Current Pharmaceutical Design
|May 22, 2012
PubMed
Summary

New anti-malarial drugs targeting phospholipid biosynthesis are needed due to resistance. Choline analogues show promise, with Albitiazolium advancing as a clinical candidate for malaria treatment.

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