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Updated: May 22, 2026

In Vivo Nanovector Delivery of a Heart-specific MicroRNA-sponge
Published on: June 15, 2018
MicroRNA regulation of lipid metabolism
Elena Flowers1, Erika Sivarajan Froelicher, Bradley E Aouizerat
1Department of Physiologic Nursing, University of California, San Francisco, School of Nursing, San Francisco, CA 94143, USA. eflowers@ucsf.edu
Abstract:
MicroRNAs are structural components of an epigenetic mechanism of post-transcriptional regulation of messenger RNA translation. Recently, there is significant interest in the application of microRNA as a blood-based biomarker of underlying physiologic conditions, and the therapeutic administration of microRNA inhibitors and mimics. The purpose of this review is to describe the current body of knowledge on microRNA regulation of genes involved in lipid metabolism, and to introduce the role of microRNA in development and progression of atherosclerosis.
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