Related Experiment Video
Updated: May 22, 2026

Granulocyte-dependent Autoantibody-induced Skin Blistering
Published on: October 12, 2012
A case of esophageal complication in epidermolysis bulhosa simplex
Catarina L Vieira1, Joao C Lopes, Ana I Lopes
1Department of Gastroenterology and Hepatology, Hospital Santa Maria, Lisboa, Portugal. rinacilv@gmail.com
Unlabelled:
It is well known the involvement of the gastrointestinal tract in Epidermolysis Bulhosa (EB) and its consequences on both nutrition and growth. We present a case of a young girl with EB diagnosed soon after birth, admitted to our emergency room with food impactation. The endoscopy revealed a double barrel esophagus. No medical or surgical therapy was started and after 2 months of enteric feeding, spontaneous resolution was observed at endoscopy. Skin biopsy was compatible with EB Simplex. According to the literature EB Simplex is the subtype the least associated with GI tract involvement, presenting with dysphagia in only 2% of the patients, and with the lowest cumulative risk of esophageal stricturing.
Conclusion:
We present an unusual case of EB simplex involvement of the esophagus with spontaneous resolution of a false lumen, with clinical improvement of the patient.
Related Concept Videos
Esophageal Strictures-I: Introduction
Etiology
The primary cause of esophageal strictures is long-standing gastroesophageal reflux disease (GERD), accounting for about 70 to 80% of adult cases. Chronic acid reflux can lead to injury and scarring of the esophageal lining, culminating in...
Esophageal Achalasia
Esophageal Perforation-I: Introduction
The location of esophageal perforation can vary, occurring anywhere along the esophagus.
Clinical Applications of Epidermal Stem Cells
Esophageal Perforation-II: Clinical Manifestations and Management
Clinical Manifestations:
Esophageal Strictures-II: Clinical Features and Management
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...