Related Experiment Video
Updated: May 22, 2026

Establishment and Confirmation of a Postnatal Right Ventricular Volume Overload Mouse Model
Published on: June 9, 2023
[Left ventricle free wall rupture - a 10-year experience]
Rui Ferreira1, J Gallego, M Mendes
1Serviço de Cardio-Torácica do Hospital de Santa Maria, CHLN, Lisboa.
Left ventricle free wall rupture, a lethal myocardial infarction complication, can be treated surgically without extracorporeal circulation. This technique offers a safer, quicker option for a previously fatal condition.
Area of Science:
- Cardiology
- Cardiac Surgery
Background:
- Left ventricle free wall rupture is a severe complication of myocardial infarction.
- It has historically high morbidity and mortality rates.
Purpose of the Study:
- To evaluate the safety and efficacy of surgical closure of left ventricle free wall rupture without extracorporeal circulation.
- To assess outcomes in patients treated between 2000 and 2010.
Main Methods:
- Retrospective analysis of 35 patients undergoing surgical repair for left ventricle free wall rupture.
- Repair involved direct closure using pericardium/synthetic patches and histoacryl glue, without cardiopulmonary bypass.
Main Results:
- Mean patient age was 69.5 years, with 65.7% males.
- Rupture occurred at a mean of 2.9 days post-infarction, frequently involving anterior/lateral walls.
- 94.7% of patients were in shock pre-operatively.
- In-hospital mortality was 28.6%, with 86% survival at 2.5 years.
- Mean ICU stay was 7.9 days.
Conclusions:
- Surgical repair of left ventricle free wall rupture without extracorporeal circulation is feasible.
- Despite high initial mortality, the procedure offers a survival benefit for a critical condition.
- The technique is relatively safe, simple, and quick, improving outcomes for patients with left ventricle free wall rupture.
More Related Videos
10:18Generation and Characterization of Right Ventricular Myocardial Infarction Induced by Permanent Ligation of the Right Coronary Artery in Mice
Published on: February 1, 2022
14:14Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement
Published on: December 11, 2017
Related Concept Videos
Aortic Regurgitation I: Introduction
Aneurysm I: Introduction
Mitral Regurgitation I: Introduction