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Updated: May 22, 2026

Noninvasive Sampling of Mucosal Lining Fluid for the Quantification of In Vivo Upper Airway Immune-mediator Levels
Published on: August 7, 2017
Serum interleukin-9 levels are associated with clinical severity in children with atopic dermatitis
Giorgio Ciprandi1, Mara De Amici, Vania Giunta
1Istituto Di Ricovero e Cura a Carattere Scientifico-Azienda Ospedaliera Universitaria San Martino di Genova, Genoa, Italy. gio.cip@libero.it
Abstract:
Atopic dermatitis (AD) is an inflammatory disorder of the skin characterized by impaired immune response. Th9 cells are a sub-population of T cells that release interleukin (IL)-9. No study has investigated the role of IL-9 in AD. This study compared 64 children with AD with 45 healthy children. Serum IL-9 levels were measured and clinical symptoms were assessed. Children with AD had higher serum IL-9 levels than controls (p = 0.01). Clinical severity was significantly related to IL-9 level, indicating that IL-9 might exert a pathogenic role in symptom occurrence in individuals with AD. Children with AD may have higher serum IL-9 levels than healthy children, and IL-9 levels are significantly related to symptom severity.
