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Related Experiment Video

Updated: May 22, 2026

Ligand Nano-cluster Arrays in a Supported Lipid Bilayer
10:34

Ligand Nano-cluster Arrays in a Supported Lipid Bilayer

Published on: April 23, 2017

"Face-lifting" and "make-up" for microorganisms: layer-by-layer polyelectrolyte nanocoating.

Rawil F Fakhrullin1, Yuri M Lvov

  • 1Department of Microbiology, Kazan (Idel buye/Volga region) Federal University, Kreml urami 18, Kazan, Republic of Tatarstan, 420008, Russia.

ACS Nano
|May 23, 2012
PubMed
Summary
This summary is machine-generated.

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Researchers engineered living cells using layer-by-layer nanoscale encapsulation. This method creates artificial microorganisms with new abilities for applications like biosensors and 3D cell clusters.

Area of Science:

  • Biotechnology and synthetic biology
  • Materials science and nanotechnology

Background:

  • Living cells can be engineered using nanoscale materials.
  • Layer-by-layer assembly is a technique for creating functional coatings.

Purpose of the Study:

  • To develop a method for encapsulating living cells using layer-by-layer assembly.
  • To explore the potential of engineered cells as artificial microorganisms.

Main Methods:

  • Sequential adsorption of oppositely charged nanoscale components onto living cells.
  • Assembly of nanoarchitectural shells under mild aqueous conditions.

Main Results:

  • Successfully created encapsulated living cells with enhanced properties.
  • Demonstrated the potential for artificial spore formation and whole-cell biosensors.

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Fabricating Reactive Surfaces with Brush-like and Crosslinked Films of Azlactone-Functionalized Block Co-Polymers
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Related Experiment Videos

Last Updated: May 22, 2026

Ligand Nano-cluster Arrays in a Supported Lipid Bilayer
10:34

Ligand Nano-cluster Arrays in a Supported Lipid Bilayer

Published on: April 23, 2017

Fabricating Reactive Surfaces with Brush-like and Crosslinked Films of Azlactone-Functionalized Block Co-Polymers
10:09

Fabricating Reactive Surfaces with Brush-like and Crosslinked Films of Azlactone-Functionalized Block Co-Polymers

Published on: June 30, 2018

Surface Passivation for Single-molecule Protein Studies
10:35

Surface Passivation for Single-molecule Protein Studies

Published on: April 24, 2014

  • Fabricated three-dimensional multicellular clusters using engineered cells.

    • Conclusions:

    • Layer-by-layer encapsulation is a viable strategy for engineering cells.
    • This approach expands the functionality of microorganisms for various applications.
    • The technique enables the creation of artificial cells and complex multicellular structures.