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Updated: May 22, 2026

Processing Embryo, Eggshell, and Fungal Culture for Scanning Electron Microscopy
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Published on: August 16, 2019

Morphogenesis of active shells.

Vladimir G Cherdantsev1, Olga V Grigorieva

  • 1Department of Biological Evolution, Faculty of Biology, Moscow State University, Moscow 119234, Russia. arnosnew@mail.ru

Bio Systems
|May 23, 2012
PubMed
Summary
This summary is machine-generated.

Active shells, like cell surfaces, exhibit self-organization and movement through surface recruitment. This research models morphogenesis, revealing self-oscillation dynamics driven by active and passive stresses in biological systems.

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Area of Science:

  • Developmental Biology
  • Biophysics
  • Morphogenesis

Background:

  • Active shells, defined as single-cell or epithelial sheets, possess properties of stretched elastic shells.
  • These shells are capable of active planar movement through the recruitment of new surface elements.
  • Morphogenesis examples include plant trichome growth and loach epiboly/dorsoventral polarity.

Purpose of the Study:

  • To model and analyze the behavior of active shells at cellular and supracellular levels.
  • To investigate the origins of mechanical stresses and self-organization in biological surfaces.
  • To understand the relationship between active/passive stresses and self-oscillation dynamics.

Main Methods:

  • Analysis of quantitative morphological data from model systems (Draba trichomes, loach epiboly).
  • Derivation of mathematical equations describing active shell behavior.
  • Comparison of derived dynamics with traditional activator-inhibitor systems.

Main Results:

  • Active shell behavior deviates from spatially homogeneous forms, generating active mechanical stresses.
  • Self-oscillation and spatial differentiation are parametrically dependent on the ratio of active to passive stresses.
  • Self-oscillation dynamics are non-local and one-parametric, with curvature as the inhibitor and spatial variance as the activator.

Conclusions:

  • The study provides a framework for understanding active shell mechanics in morphogenesis.
  • Linear ontogeny is proposed as a secondary evolutionary outcome of cyclic self-organizing algorithms.
  • This work offers insights into the fundamental principles governing biological shape formation and evolution.