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Complex microtubule structures are present in resting cells and in dividing cells. In resting cells, they are responsible for maintaining the cellular architecture, tracks for intracellular transport, positioning of organelles, assembly of cilia and flagella. They mediate the bipolar spindle assembly for chromosomal segregation and positioning of the cell division plate in dividing cells. The formation of microtubule complex structures depends on the cell type, cell stage, and cell function.
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Self-assembly of Complex Two-dimensional Shapes from Single-stranded DNA Tiles
10:23

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Using shape for self-assembly.

Ludovico Cademartiri1, Kyle J M Bishop, Phillip W Snyder

  • 1Department of Chemistry and Chemical Biology, Harvard University, 12 Oxford Street, Cambridge, MA 02138, USA. lcademar@iastate.edu

Philosophical Transactions. Series A, Mathematical, Physical, and Engineering Sciences
|May 23, 2012
PubMed
Summary
This summary is machine-generated.

Alan Mackay

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Area of Science:

  • Interdisciplinary science
  • Materials science
  • Biophysics

Background:

  • Alan Mackay's lifelong pursuit of understanding morphogenesis and form.
  • His interdisciplinary approach integrating chemistry, physics, mathematics, and biology.
  • The challenge of thinking uniquely about complex problems.

Purpose of the Study:

  • To explore nanoscale self-assembly through Mackay's unique perspective.
  • To consider form and shape in the context of self-assembly.
  • To extend Mackay's 'beyond crystals' theme to the nanoscale.

Main Methods:

  • Conceptual exploration inspired by Alan Mackay's work.
  • Application of interdisciplinary principles to nanoscale phenomena.
  • Analysis of form and shape in self-assembling systems.

Main Results:

  • Mackay's approach offers novel insights into nanoscale self-assembly.
  • The importance of form and shape is highlighted in self-assembly.
  • An interdisciplinary framework is proposed for studying self-assembly.

Conclusions:

  • Mackay's visionary thinking provides a valuable lens for nanoscale self-assembly.
  • Further research integrating diverse scientific fields is encouraged.
  • Understanding form and shape is crucial for controlling self-assembly.