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Related Concept Videos

Factors Affecting the Risk of Infection01:26

Factors Affecting the Risk of Infection

The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin create...
The Tumor Microenvironment02:17

The Tumor Microenvironment

Every normal cell or tissue is embedded in a complex local environment called stroma, consisting of different cell types, a basal membrane, and blood vessels. As normal cells mutate and develop into cancer cells, their local environment also changes to allow cancer progression. The tumor microenvironment (TME) consists of a complex cellular matrix of stromal cells and the developing tumor. The cross-talk between cancer cells and surrounding stromal cells is critical to disrupt normal tissue...
Healing II: Complications01:24

Healing II: Complications

Complications during healing arise when tissue repair is altered by local or systemic factors. These changes involve abnormal collagen deposition, altered biomechanics, and reduced vascular supply, impairing restoration of normal structure and function.Loss of FunctionScar tissue differs significantly from the original tissue it replaces. In the skin, fibrosis lacks adnexal structures such as hair follicles, sebaceous glands, and sweat glands. Their absence reduces tactile sensitivity, impairs...
Colonisation of Pathogens01:25

Colonisation of Pathogens

Pathogen colonization of host tissues is a critical step in the development of infectious diseases. Various pathogenic microorganisms, including bacteria, fungi, viruses, and protozoa, have evolved complex strategies to attach to, invade, and persist within host environments. These mechanisms enable pathogens to establish infections, evade immune responses, and resist antimicrobial treatments.Attachment to Host CellsIn bacteria, colonization typically begins with adherence to host epithelial...
Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic01:26

Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic

Healthcare-associated infections (HAIs) occur in a healthcare facility while a person receives care for another ailment. This category also includes work-related infections among healthcare staff.
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Related Experiment Video

Updated: May 22, 2026

Endoscopic Bilateral Nipple-sparing Mastectomy via a Single Axillary Incision with Immediate Pre-pectoral Implant-based Breast Reconstruction
13:35

Endoscopic Bilateral Nipple-sparing Mastectomy via a Single Axillary Incision with Immediate Pre-pectoral Implant-based Breast Reconstruction

Published on: May 17, 2024

Contributing variables to post mastectomy tissue expander infection.

Mark M Leyngold1, Ross L Stutman, Kayvan T Khiabani

  • 1Division of Plastic Surgery, Department of Surgery, University of Nevada School of Medicine, Las Vegas, Nevada 89102-2227, USA.

The Breast Journal
|May 24, 2012
PubMed
Summary
This summary is machine-generated.

Postoperative breast cellulitis and inpatient procedures significantly increase the risk of infection in tissue expander breast reconstruction. Other patient factors did not show a statistically significant impact on prosthetic infection rates.

Related Experiment Videos

Last Updated: May 22, 2026

Endoscopic Bilateral Nipple-sparing Mastectomy via a Single Axillary Incision with Immediate Pre-pectoral Implant-based Breast Reconstruction
13:35

Endoscopic Bilateral Nipple-sparing Mastectomy via a Single Axillary Incision with Immediate Pre-pectoral Implant-based Breast Reconstruction

Published on: May 17, 2024

Area of Science:

  • Plastic Surgery
  • Reconstructive Surgery
  • Infectious Disease

Background:

  • Tissue expander breast reconstruction is a frequent procedure following mastectomy.
  • Understanding infection risks is crucial for optimizing patient outcomes.

Purpose of the Study:

  • To determine the incidence of prosthetic infection after tissue expander breast reconstruction.
  • To identify patient characteristics and postoperative complications associated with increased infection rates.

Main Methods:

  • Retrospective chart review of 195 women undergoing tissue expander/implant reconstruction.
  • Analysis of patient factors, operative techniques, and complications using binary logistic regression.

Main Results:

  • Overall periprosthetic infection rate was 5.1% per patient and 3.2% per breast.
  • Postoperative breast cellulitis increased infection odds over 200-fold (p < 0.0001).
  • Inpatient procedures increased infection odds 16-fold (p = 0.02).

Conclusions:

  • Postoperative breast cellulitis and inpatient status are significant risk factors for periprosthetic infection.
  • Other analyzed variables, including age, diabetes, and smoking, did not reach statistical significance.