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Construction of Cell-based Neurotransmitter Fluorescent Engineered Reporters (CNiFERs) for Optical Detection of Neurotransmitters In Vivo
Published on: May 12, 2016
Real-time stochastic detection of multiple neurotransmitters with a protein nanopore
Arnold J Boersma1, Keith L Brain, Hagan Bayley
1Department of Chemistry, University of Oxford, Oxford, OX1 3TA, United Kingdom.
ACS Nano
|May 24, 2012
Abstract:
The detection of several different neurotransmitters with the same sensor in real-time would be a powerful asset to the field of neurochemistry. We have developed a detector for a broad range of neurotransmitters including amino acids, catecholamines, and nucleotides, which relies on the reversible binding of the analytes to a copper(II) complex within an engineered protein nanopore.
