Related Experiment Video
Updated: May 22, 2026
Full-Field Optical Coherence Microscopy for Histology-Like Analysis of Stromal Features in Corneal Grafts
Published on: October 21, 2022
[Estimation of postmortem interval by detecting thickness of cornea using ultrasonic method]
Guo-Li Lü1, Fu-Xue Jiang, Xin-Shu Xu
1Guangzhou Institute of Criminal Science and Technology, Guangzhou 510030, China. guolil@sina.com
Objective:
To explore the postmortem changes of cornea thickness measured by ultrasonic pachymetry.
Methods:
Eleven rabbits were randomly divided into two groups: one group with intact corneal epithelium and another group without intact corneal epithelium. In the later group, the corneal epithelium of the rabbit was scraped using mechanical elimination method. The corneal thickness was monitored continuously by ultrasonic pachymetry at several postmortem interval points in rabbits of the two groups. The changes of corneal thickness and postmortem interval were explored by relative regression analysis.
Results:
The thickness of the cornea showed a strong non-linear correlation with the postmortem interval in the group with intact corneal epithelium. The group with intact corneal epithelium showed the correlation coefficient 0.922 and the group without intact corneal epithelium showed the correlation coefficient 0.822, respectively.
Conclusion:
The corneal thickness measured by ultrasonic pachymetry shows a potential value for estimating early postmortem interval. The intact corneal epithelium is a crucial factor for the measurement of cornea thickness by ultrasonic pachymetry.
