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Updated: May 22, 2026

Point-Of-Care Ultrasound Screening for Proximal Lower Extremity Deep Venous Thrombosis
Published on: February 10, 2023
[Cockett's syndrome, May-Thurner syndrome, or iliac vein compression syndrome]
A R Gil Martín1, M Carreras Aja1, I Arrieta Ardieta1
1Servicio de Radiología, Hospital de Cruces, Barakaldo, Vizcaya, España.
Insights
May-Thurner syndrome, or iliac vein compression, occurs when the left common iliac vein is compressed, leading to blood flow obstruction and thrombus formation. Endovascular angioplasty and stenting are the preferred treatments to restore venous drainage.
Area of Science:
- Vascular Surgery
- Interventional Radiology
- Cardiovascular Medicine
Background:
- Iliac vein compression syndrome (IVCS), also known as May-Thurner syndrome, is a rare condition where the left common iliac vein is compressed between the right common iliac artery and the spine.
- This chronic compression can lead to intimal damage, venous stenosis, and potentially deep vein thrombosis (DVT).
Observation:
- The pulsatile force of the right common iliac artery on the left common iliac vein causes sustained trauma.
- This trauma can result in the formation of intraluminal membranes or bands, significantly hindering venous blood flow.
- Clinical presentation may include symptoms suggestive of DVT or chronic venous insufficiency.
Findings:
- Computed tomography (CT) imaging is crucial for diagnosing IVCS, revealing characteristic findings of venous compression and potential intraluminal abnormalities.
- Endovascular treatment, including vein patch angioplasty and stenting, is the current gold standard for managing IVCS.
- Successful treatment aims to relieve compression, improve venous lumen caliber, and restore normal venous outflow.
Implications:
- Effective management of May-Thurner syndrome can prevent complications such as post-thrombotic syndrome and pulmonary embolism.
- Early diagnosis and intervention are key to optimizing patient outcomes and quality of life.
- Further research into the long-term efficacy and optimal techniques for endovascular repair is warranted.
Abstract:
Iliac vein compression syndrome (also known as May-Thurner syndrome or Cockett's syndrome) is a rare clinical entity in which the left common iliac vein is compressed when it passes between the right common iliac artery and the spine. The sustained compression and trauma caused by the pulsatile force of the artery on the vein damage the intima and lead to the formation of membranes or bands in the vascular lumen that hinder or obstruct the flow of blood in the vein, favoring thrombus formation. The current treatment strategy of choice is endovascular vein patch angioplasty and stenting with the aim of improving the caliber of the lumen and enabling normal venous drainage. We present two cases of May-Thurner syndrome and review the clinical and CT findings.
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