Primary malignant melanoma of proximal tibia

Area of Science:

• Orthopedic Oncology
• Skeletal Neoplasms
• Melanoma Research

Background:

• Primary malignant melanoma of bone is exceptionally rare, with fewer than ten cases documented.
• Metastatic melanoma to bone is more common than primary bone melanoma.

Observation:

• A 26-year-old woman presented with primary malignant melanoma of the proximal tibia.
• The tumor arose from the medial aspect of the proximal tibia.

Findings:

• The patient underwent above-knee amputation as the sole treatment.
• No chemotherapy or radiotherapy was administered.
• The patient remained disease-free at an 18-month follow-up.

Implications:

• This case adds to the limited literature on primary bone melanoma.
• Amputation alone may be a viable treatment option for select cases.
• Further research is needed to understand this rare bone cancer.