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Infantile hemangiopericytoma of the orbit treated with primary chemotherapy
Neelam Pushker1, Dinesh Shrey, Sameer Bakhshi
1Oculoplasty and Paediatric Ophthalmology Services, All India Institute of Medical Sciences, New Delhi, India.
Insights
A rare infantile hemangiopericytoma caused left eye proptosis in an infant. Chemotherapy effectively treated the tumor, with no recurrence observed 14 months post-treatment.
Area of Science:
- Ophthalmology
- Pediatric Oncology
- Pathology
Background:
- Orbital tumors are rare in infants, presenting diagnostic challenges.
- Infantile hemangiopericytoma is an uncommon vascular tumor typically affecting soft tissues.
Observation:
- A 7-month-old female infant presented with proptosis (bulging) of the left eye.
- Ophthalmic imaging revealed an intraconal orbital mass with significant post-contrast enhancement, suggesting a hypervascular tumor.
Findings:
- Histopathological examination confirmed the diagnosis of infantile hemangiopericytoma.
- Primary chemotherapy was administered as the initial treatment modality.
- The patient remained disease-free with no recurrence for 14 months after completing chemotherapy.
Implications:
- This case highlights the importance of considering rare orbital tumors in pediatric proptosis.
- Chemotherapy can be an effective primary treatment for infantile hemangiopericytoma, potentially avoiding more invasive procedures.
- Long-term surveillance is crucial to monitor for any late recurrences of this tumor.
Abstract:
A 7-month-old female infant presented with proptosis of the left eye. Imaging showed an intraconal mass with marked post-contrast enhancement. Histopathology revealed a diagnosis of infantile hemangiopericytoma. The patient was treated with primary chemotherapy with no recurrence until 14 months after completion of treatment.