Infantile hemangiopericytoma of the orbit treated with primary chemotherapy

Neelam Pushker1, Dinesh Shrey, Sameer Bakhshi

  • 1Oculoplasty and Paediatric Ophthalmology Services, All India Institute of Medical Sciences, New Delhi, India.

Insights

A rare infantile hemangiopericytoma caused left eye proptosis in an infant. Chemotherapy effectively treated the tumor, with no recurrence observed 14 months post-treatment.

Area of Science:

  • Ophthalmology
  • Pediatric Oncology
  • Pathology

Background:

  • Orbital tumors are rare in infants, presenting diagnostic challenges.
  • Infantile hemangiopericytoma is an uncommon vascular tumor typically affecting soft tissues.

Observation:

  • A 7-month-old female infant presented with proptosis (bulging) of the left eye.
  • Ophthalmic imaging revealed an intraconal orbital mass with significant post-contrast enhancement, suggesting a hypervascular tumor.

Findings:

  • Histopathological examination confirmed the diagnosis of infantile hemangiopericytoma.
  • Primary chemotherapy was administered as the initial treatment modality.
  • The patient remained disease-free with no recurrence for 14 months after completing chemotherapy.

Implications:

  • This case highlights the importance of considering rare orbital tumors in pediatric proptosis.
  • Chemotherapy can be an effective primary treatment for infantile hemangiopericytoma, potentially avoiding more invasive procedures.
  • Long-term surveillance is crucial to monitor for any late recurrences of this tumor.

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