Related Experiment Video
Updated: May 22, 2026
07:40
Multi-Modal Home Sleep Monitoring in Older Adults
Published on: January 26, 2019
Sleep disorders and multiple sclerosis: a clinical and polysomnography study.
Jean-Philippe Neau1, Joël Paquereau, Vanessa Auche
1Department of Neurology, CHU La Milétrie, Poitiers, France. jph.neau@chu-poitiers.fr
European Neurology
|May 26, 2012
Summary
Sleep disturbances and excessive daytime sleepiness are common in multiple sclerosis (MS). Poor sleepers in MS require prompt evaluation and treatment to enhance their quality of life.
Area of Science:
- Neurology
- Sleep Medicine
- Quality of Life Research
Background:
- Patients with multiple sclerosis (MS) experience higher rates of sleep disturbances (SD) and excessive daytime sleepiness (EDS) compared to the general population.
- The study aimed to assess SD and EDS in MS patients and validate subjective sleep assessment tools.
Purpose of the Study:
- To evaluate the prevalence and characteristics of sleep disturbances and excessive daytime sleepiness in multiple sclerosis patients.
- To assess the reliability of subjective sleep questionnaires in this population.
- To explore correlations between sleep issues, clinical factors, and quality of life in MS.
Main Methods:
- Collected demographic and clinical data from 205 unselected MS patients.
- Utilized various questionnaires for sleep quality, daytime sleepiness, fatigue, anxiety, depression, and quality of life (QoL).
- Conducted polysomnography and Multiple Sleep Latency Test (MSLT) in 25 selected MS patients.
Main Results:
- Over half of the MS patients were identified as 'poor sleepers'.
- Sleep disturbances were significantly correlated with disability, fatigue, depression, QoL, and pain, but not with excessive daytime sleepiness.
- Subjective sleepiness (Epworth Sleepiness Scale) and sleep quality (Pittsburgh Sleep Quality Index) did not correlate with objective vigilance (MSLT) or sleep assessments.
Conclusions:
- Sleep disturbances and excessive daytime sleepiness are prevalent in multiple sclerosis.
- Objective assessment of sleep and vigilance in MS can be complex.
- MS patients identified as poor sleepers warrant immediate assessment and intervention to improve their overall quality of life.
Related Concept Videos
01:19Multiple Sclerosis l: Introduction
Multiple sclerosis is a chronic autoimmune disease of the central nervous system (CNS) that affects the brain, spinal cord, and optic nerves. It is an inflammatory demyelinating disorder and a leading cause of neurological disability in young adults.EpidemiologyMS commonly begins between 20 and 40 years of age and is twice as common in women. Its exact cause remains unclear, but genetic susceptibility contributes, with higher risk in first-degree relatives and identical twins. A greater...
01:15REM Sleep Behavior Disorder
REM Sleep Behavior Disorder (RBD) is a sleep disorder characterized by the absence of muscle paralysis that normally occurs during the REM phase of sleep. This absence allows individuals to physically act out their dreams, which are often vivid and disturbing. Common behaviors exhibited during episodes include kicking, punching, and yelling. These actions can be dangerous, potentially leading to injuries for the person with RBD or their bed partner.
RBD is significantly associated with...
RBD is significantly associated with...
01:07Narcolepsy
Narcolepsy is a chronic sleep disorder characterized by pervasive, uncontrolled sleepiness and other sleep disturbances. One of its hallmark symptoms is an abrupt transition to REM sleep upon falling asleep, which causes symptoms typically associated with this phase to occur unexpectedly during wakefulness. These include the following symptoms, which typically last from a minute or two to half an hour.
01:24Sleep-Wake Cycles
Sleep is an essential physiological process vital to maintaining overall well-being. The reticular activating system (RAS), a network of neurons in the brainstem, regulates wakefulness and sleep. While it may seem passive, sleep consists of distinct cycles, each with its unique characteristics and functions. Two key sleep phases are non-rapid eye movement (NREM) and rapid eye movement (REM).
NREM Sleep
NREM sleep comprises four progressive stages that seamlessly merge:
NREM Sleep
NREM sleep comprises four progressive stages that seamlessly merge:
01:19Management of Insomnia
The sleep cycle, an integral part of human health, consists of several stages with distinct characteristics and functions. It begins with a transition from wakefulness to sleep, known as the light sleep phase, followed by the restorative deep sleep phase, essential for physical recovery and growth. The cycle concludes with the Rapid Eye Movement (REM) phase, characterized by high brain activity and vivid dreaming. Insomnia, a prevalent sleep disorder, involves difficulty falling asleep, staying...
01:18Nightmares and Night Terrors
Nightmares and night terrors represent two distinct types of sleep disturbances that differ in timing, characteristics, and the sleeper's recall of the event. Nightmares are vivid, disturbing dreams that usually awaken the sleeper from REM sleep, a stage of sleep where brain activity is high, and dreams are most frequent. Upon awakening, individuals often have detailed recollections of their nightmares, which can include themes of threats to survival, security, or self-esteem.
Nightmares often...
Nightmares often...