Related Experiment Video
Updated: May 22, 2026
06:15
Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia
Published on: August 9, 2024
Low-grade central osteosarcoma of the orbit
Reiji Morita1, Kenichi Shimada, Shigehiko Kawakami
1Department of Plastic and Reconstructive Surgery, Kanazawa Medical University, Ishikawa, Japan. rei@kanazawa-med.ac.jp
The Journal of Craniofacial Surgery
|May 26, 2012
Summary
Low-grade central osteosarcoma, a rare bone cancer, can occur in the orbit. This report details a unique orbital case, its diagnosis, and successful surgical treatment.
Area of Science:
- Oncology
- Orthopedic Surgery
- Ophthalmology
Background:
- Low-grade central osteosarcoma (LGCO) is a rare malignant bone tumor, comprising less than 2% of all osteosarcomas.
- LGCO predominantly affects long bones, particularly the tibia, and is exceptionally uncommon in craniofacial bones.
Observation:
- This report presents a unique case of LGCO originating in the orbit, a location previously undocumented for this tumor type.
- The tumor's presentation and diagnostic challenges are discussed.
Findings:
- The study details the differential diagnoses considered for this orbital tumor.
- Successful radical resection and reconstruction were achieved, highlighting effective surgical management.
Implications:
- This case expands the known anatomical distribution of LGCO.
- It underscores the importance of considering rare diagnoses in orbital oncology and demonstrates the feasibility of surgical intervention.
Related Concept Videos
01:25Glaucoma: Overview
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
01:27Open Angle Glaucoma: Treatment
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
01:27Cranial Bones: Lateral View
The lateral view of the cranium is dominated by temporal, sphenoid, and ethmoid bones.
The temporal bone forms the lower lateral side of the skull. The temporal bone is subdivided into several regions. The flattened upper portion is the squamous portion of the temporal bone. Below this area and projecting anteriorly is the zygomatic process of the temporal bone, which forms the posterior portion of the zygomatic arch. Posteriorly is the mastoid portion of the temporal bone. Projecting...
The temporal bone forms the lower lateral side of the skull. The temporal bone is subdivided into several regions. The flattened upper portion is the squamous portion of the temporal bone. Below this area and projecting anteriorly is the zygomatic process of the temporal bone, which forms the posterior portion of the zygomatic arch. Posteriorly is the mastoid portion of the temporal bone. Projecting...
01:28Angle Closure Glaucoma: Treatment
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
01:17Accessory Structures of the Eye
Optical perception, or vision, is an extraordinary sense dependent on converting light signals received via the ocular organs. These organs, known as eyes, are securely positioned within the bony cavities of the skull, called orbits. The orbits serve a dual purpose: a protective shield for the ocular globes and a stable attachment point for the soft ocular tissues. The eye's external protective mechanisms include the eyelids, which are edged with lashes that act as a barrier against foreign...