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Updated: May 22, 2026

Three-Dimensional Collagen Matrix Scaffold Implantation as a Liver Regeneration Strategy
Published on: June 29, 2021
New collagen matrix to avoid the reduction of keratinized tissue during guided bone regeneration in postextraction
Daniele De Santis1, Alessandro Cucchi, Antonio de Gemmis
1Section of Dentistry and Maxillofacial Surgery, Department of Morphological and Biomedical Sciences, University of Verona, Verona, Italy. dds.univr@hotmail.it
Abstract:
For decades, there has been an ongoing controversy regarding the need for an "adequate" width of keratinized gingiva/mucosa to preserve periodontal and implant health. Today, the presence of a certain width of keratinized tissue is recommended for achieving long-term periodontal and implant success, and therefore, a new collagen matrix has been developed to enhance the width of keratinized gingiva/mucosa. During postextraction socket preservation, guided bone regeneration techniques require complete coverage of the barrier membrane to reduce the risk of infection, occasionally causing a reduction of the width of keratinized tissue. Using the new collagen matrix, it is possible to leave the membrane intentionally uncovered, without suturing the surgical flap above it, to avoid the reduction of such tissue.
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