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Related Concept Videos

Counterfactual Thinking01:19

Counterfactual Thinking

Counterfactual thinking is a cognitive process wherein individuals mentally reconstruct alternative versions of past events, often beginning with “what if” or “if only.” This reflective mechanism plays a significant role in shaping emotional experiences and guiding future behavior. Though typically triggered by unfavorable or unexpected outcomes, counterfactual thinking can also emerge in mundane, everyday decisions and experiences, revealing its deep entrenchment in human cognition.Types of...
Forced Transdifferentiation01:28

Forced Transdifferentiation

Transdifferentiation, also known as lineage reprogramming, was first discovered by Selman and Kafatos in 1974 in silkmoths. They observed that the moths’ cuticle-producing cells transformed into salt-producing cells. Many such cases of natural transdifferentiation occur in organisms. In humans, pancreatic alpha cells can become beta cells. In newts, the loss of the eye’s lens causes the pigmented epithelial cells to transdifferentiate into the lens cells.
Artificial transdifferentiation occurs...
Source Transformation01:15

Source Transformation

Source transformation is a fundamental technique employed in circuit analysis, offering a valuable tool for simplifying complex electrical circuits. This technique involves the replacement of either a voltage source in series with a resistor by a current source in parallel with a resistor, or vice versa. The key concept here is that when the original sources are deactivated (turned off), the equivalent resistance at the circuit's end terminals remains the same.
It is essential to note that when...
The Scientific Method02:40

The Scientific Method

Research is what makes the difference between facts and opinions. Facts are observable realities, and opinions are personal judgments, conclusions, or attitudes that may or may not be accurate. In the scientific community, facts can be established only using evidence collected through empirical research.
Ethics in Research01:56

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Today, scientists agree that good research is ethical in nature and is guided by a basic respect for human dignity and safety. However, this has not always been the case. Modern researchers must demonstrate that the research they perform is ethically sound.
Bacterial Transformation01:33

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In 1928, bacteriologist Frederick Griffith worked on a vaccine for pneumonia, which is caused by Streptococcus pneumoniae bacteria. Griffith studied two pneumonia strains in mice: one pathogenic and one non-pathogenic. Only the pathogenic strain killed host mice.
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Enactive Phenomenological Approach to the Trier Social Stress Test: A Mixed Methods Point of View
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Published on: January 7, 2019

Transformative research: definitions, approaches and consequences.

J T Trevors1, Gerald H Pollack, Milton H Saier

  • 1School of Environmental Sciences, University of Guelph, 50 Stone Road, East, Guelph, ON N1G 2W1, Canada. jtrevors@uoguelph.ca

Theory in Biosciences = Theorie in Den Biowissenschaften
|May 26, 2012
PubMed
Summary
This summary is machine-generated.

Transformative research (TR) fundamentally alters scientific thinking, often involving intuition, serendipity, and collaboration. Understanding these elusive elements is key to advancing knowledge across disciplines.

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Last Updated: May 22, 2026

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Area of Science:

  • Scientific methodology and innovation
  • Interdisciplinary research studies

Background:

  • Transformative research (TR) is challenging to define and achieve.
  • Existing research frameworks may not fully capture the nature of TR.

Purpose of the Study:

  • To propose and discuss a definition of transformative research.
  • To elucidate the characteristics and contributing factors of TR.

Main Methods:

  • Conceptual analysis and definition.
  • Illustrative examples of TR unfolding.
  • Highlighting contributions to knowledge.

Main Results:

  • TR is defined as research that transforms thought patterns in a scientific field.
  • Key elements include intuition, serendipity, and interpersonal communication.
  • TR can be elusive and requires unique approaches.

Conclusions:

  • TR significantly advances both basic and applied humanistic knowledge.
  • Recognizing and fostering TR is crucial for scientific progress.
  • The proposed definition provides a framework for understanding TR.