Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Halothane hepatitis in children.

E Hassall1, D M Israel, T Gunasekaran

  • 1Department of Pediatrics, University of British Columbia, Vancouver, Canada.

Journal of Pediatric Gastroenterology and Nutrition
|November 1, 1990
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Transvenous occlusion of a patent ductus arteriosus in a cat with the Amplatzer™ Vascular Plug II.

Journal of veterinary cardiology : the official journal of the European Society of Veterinary Cardiology·2026
Same author

Repeatability and reproducibility of feline echocardiographic left ventricular myocardial area and left ventricular wall thickness measurement techniques.

Journal of veterinary cardiology : the official journal of the European Society of Veterinary Cardiology·2026
Same author

Assessment of heart rate measurements obtained from smartphone electrocardiography as compared to 24-h Holter monitoring in dogs with atrial fibrillation.

Journal of veterinary cardiology : the official journal of the European Society of Veterinary Cardiology·2025
Same author

Determining the optimal Holter monitoring duration for detecting ventricular arrhythmia in dogs: a Bayesian approach.

Journal of veterinary cardiology : the official journal of the European Society of Veterinary Cardiology·2025
Same author

Assessment of heart rate measurements obtained from a smart collar compared to 24-h Holter monitoring in healthy dogs.

Journal of veterinary cardiology : the official journal of the European Society of Veterinary Cardiology·2024
Same author

Successful balloon angioplasty in a cat with unilateral left pulmonary artery branch stenosis.

Journal of veterinary cardiology : the official journal of the European Society of Veterinary Cardiology·2023
Same journal

Heterogeneous outcomes in pediatric potential celiac disease: A multicenter longitudinal study.

Journal of pediatric gastroenterology and nutrition·2026
Same journal

Inter-tissue relationships of gene expression in liver, muscle and adipose tissue of children with end-stage chronic liver disease.

Journal of pediatric gastroenterology and nutrition·2026
Same journal

Foreign body ingestions in children and adolescents: A position paper of the European Society for Pediatric Gastroenterology, Hepatology, and Nutrition (ESPGHAN) endoscopy special interest group.

Journal of pediatric gastroenterology and nutrition·2026
Same journal

Abdominal pain in pediatric immunoglobulin A vasculitis: Risk factors and severity predictors in a multicenter cohort.

Journal of pediatric gastroenterology and nutrition·2026
Same journal

Cognitive assessment in children with intestinal failure on and weaned off parenteral nutrition.

Journal of pediatric gastroenterology and nutrition·2026
Same journal

Safety of infant milks: Contamination with cereulide. A commentary by ESPGHAN (European Society for Paediatric Gastroenterology, Hepatology, and Nutrition).

Journal of pediatric gastroenterology and nutrition·2026
See all related articles

Halothane hepatitis, a liver injury from anesthesia, can occur in children, contrary to common belief. This study highlights varied presentations like jaundice or fever after halothane exposure.

Area of Science:

  • Hepatology
  • Pediatric Anesthesiology

Background:

  • Halothane hepatitis is recognized in adults, but often considered rare in children.
  • Clinical experience suggests halothane hepatitis may occur in pediatric patients.

Observation:

  • Two pediatric cases of cholestatic hepatitis post-halothane anesthesia are presented.
  • Presentations included delayed jaundice after multiple exposures and prolonged fever after a single exposure.

Findings:

  • Clinical presentations of halothane hepatitis in children can vary, including delayed jaundice or fever.
  • Halothane-specific antibodies were positive in one case and negative in another, complicating diagnosis.
  • Diagnosis is primarily clinical, requiring exclusion of other liver diseases and a high index of suspicion.

Related Experiment Videos

Implications:

  • Halothane hepatitis, though uncommon, does occur in children and may not present as fulminant hepatic failure.
  • Avoiding further halothane exposure and obtaining halothane-specific antibody tests are crucial if suspected.
  • Detailed patient history and timely diagnosis are essential for managing pediatric halothane hepatitis.