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Published on: October 29, 2014

[The ileocoecal valve changes in chronic constipation in children]

R Sh Polukhov

    Klinichna Khirurhiia
    |May 29, 2012
    PubMed

    Insights

    This study found that magnesium orotate treatment effectively resolved chronic constipation in most children with ileocecal valve insufficiency. Younger patients generally showed better outcomes from conservative management.

    Area of Science:

    • Pediatric Gastroenterology
    • Colorectal Surgery
    • Pharmacology

    Context:

    • Chronic constipation affects children with anatomical large bowel anomalies.
    • Ileocecal valve (IV) insufficiency is a specific condition noted in some pediatric cases.
    • Evaluating treatment efficacy for complex pediatric gastrointestinal issues is crucial.

    Purpose:

    • To assess the effectiveness of conservative treatment, including magnesium orotate, for chronic constipation in children with anatomical large bowel anomalies and IV insufficiency.
    • To determine the success rate of conservative versus surgical interventions.
    • To explore the relationship between patient age and treatment outcomes.

    Summary:

    • A study analyzed 574 children with chronic constipation due to large bowel anomalies, identifying 61 with ileocecal valve (IV) insufficiency.
    • Patients received conservative treatment including magnesium orotate to address IV insufficiency.
    • Conservative treatment was effective in 91.8% of cases, with only 5 requiring surgery, indicating a negative correlation between age and treatment success.

    Impact:

    • Highlights the efficacy of magnesium orotate in managing pediatric chronic constipation associated with IV insufficiency.
    • Suggests conservative management is highly successful, reducing the need for surgical intervention in many cases.
    • Provides evidence for age-related differences in treatment response for this pediatric population.

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