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The total synthesis of (-)-aurafuron A

Olaf Hartmann1, Markus Kalesse

  • 1Institut für Organische Chemie and Centre of Biomolecular Drug Research (BMWZ), Leibniz Universität Hannover, Schneiderberg 1B, 30167 Hannover, Germany.

Organic Letters
|May 29, 2012
PubMed
Summary

The first total synthesis of (-)-aurafuron A was achieved using key Suzuki coupling and anionic aldol reactions. This synthesis confirms the molecule's structure and configuration, enabling further structure-activity relationship studies.

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