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Updated: May 22, 2026

Tissue Collection and RNA Extraction from the Human Osteoarthritic Knee Joint
Published on: July 22, 2021
Total joint arthroplasty for persons with osteoarthritis
Christopher W Grayson1, Robert C Decker
1Department of Orthopaedics and Rehabilitation, University of Florida, Gainesville, FL, USA.
As Americans live longer, osteoarthritis treatment needs rise, but surgeon numbers decline. This review details joint replacement outcomes to guide nonoperative care and patient education.
Area of Science:
- Orthopedics
- Geriatric Medicine
- Surgical Outcomes
Background:
- Aging populations increase demand for osteoarthritis treatment.
- Projected decline in orthopedic surgeons performing joint replacement surgery.
- Growing need for nonoperative physician expertise in osteoarthritis management.
Purpose of the Study:
- Review surgical options for major joint arthroplasty.
- Detail joint-specific indications and outcomes for arthroplasty procedures.
- Inform nonoperative physicians on optimizing patient care and surgical education.
Main Methods:
- Review of current literature on total joint arthroplasty outcomes.
- Analysis of joint-specific success rates for pain relief and functional improvement.
- Comparison of outcomes across hip, knee, shoulder, elbow, and ankle arthroplasty.
Main Results:
- Total hip and knee arthroplasty show the best outcomes for pain and function.
- Shoulder arthroplasty demonstrates encouraging but less robust outcomes.
- Elbow and ankle arthroplasty have more limited functional gains and higher complication risks, with ankle fusion often preferred.
Conclusions:
- Arthroplasty outcomes vary significantly by joint.
- Nonoperative management and patient education are crucial due to surgeon shortages.
- Understanding joint-specific results is key for informed treatment decisions in osteoarthritis.
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