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Use of Rabbit Eyes in Pharmacokinetic Studies of Intraocular Drugs
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Use of Rabbit Eyes in Pharmacokinetic Studies of Intraocular Drugs

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[Human alfa-2b in rabbit's eyes]

L Prata1, A Folgado, J Maia-Seco

  • 1Instituto de Oftalmologia, Universidade de Lisboa, Portugal.

Ophtalmologie : Organe De La Societe Francaise D'Ophtalmologie
|July 1, 1990
PubMed

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Epistasis01:39

Epistasis

In addition to multiple alleles at the same locus influencing traits, numerous genes or alleles at different locations may interact and influence phenotypes in a phenomenon called epistasis. For example, rabbit fur can be black or brown depending on whether the animal is homozygous dominant or heterozygous at a TYRP1 locus. However, if the rabbit is also homozygous recessive at a locus on the tyrosinase gene (TYR), it will have an unshaded coat that appears white, regardless of its TYRP1...