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Updated: May 22, 2026
Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis
Published on: February 6, 2021
[Bacterial endophthalmitis: retrospective clinical and microbiological study in Rabat Specialty Hospital]
S Marcil1, H Kabbaj, O Cherkaoui
1Faculté de Médecine et de Pharmacie, Université Mohamed V Souissi, Rabat Institut, BP 6203, avenue Mohamed Belarbi El Alaoui, Rabat, Maroc. sarrah_marcil@yahoo.fr
Objectives:
To study and discuss the epidemiological, clinical, microbiological, and risk factors of bacterial endophthalmitis treated in the Rabat Specialty Hospital ophthalmology department.
Patients And Methods:
This is a retrospective study over a period of 10 months of patients hospitalized for suspected acute infectious endophthalmitis. An intake form was completed for each patient. Each sample underwent direct examination and culture. All patients underwent the same protocol, providing for at least one intravitreal antibiotic injection and instillation of fortified eye drops.
Results:
Twenty cases of endophthalmitis were recorded during the study period. Decreased visual acuity, intraocular inflammation, pain and conjunctival hyperemia were found in all patients. The median onset of symptoms was 4 days. Vitreous tap or anterior chamber paracentesis was performed in all patients. Bacteria were found in seven samples (40%). Gram positive organisms accounted for 85% of positive cultures. Amphotericin B was required in four patients, and systemic antibiotic therapy in ten patients. Corticosteroid treatment was administered secondarily in eight patients.
Discussion:
In this retrospective series, epidemiological, clinical and microbiological data are consistent with those already published.
