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Updated: May 22, 2026

Patch Clamp Recording of Starburst Amacrine Cells in a Flat-mount Preparation of Deafferentated Mouse Retina
Published on: October 13, 2016
A color-coding amacrine cell may provide a blue-off signal in a mammalian retina
1Unit on Retinal Neurophysiology, National Eye Institute, US National Institutes of Health, Bethesda, Maryland, USA.
Abstract:
Retinal amacrine cells are thought to lack chromatic or color-selective light responses and have only a minor role in color processing. We found that a type of mammalian (Ictidomys tridecemlineatus) amacrine cell selectively carries a blue-On signal, which is received from a blue or short wavelength-sensitive (S) cone On bipolar cell. This glycinergic inhibitory S-cone amacrine cell is ideally placed for driving blue-Off responses in downstream ganglion cells.
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