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[Familial complete atrioventricular block of adult onset]
Y Tsuchioka1, H Nakagawa, T Kawagoe
11st Department of Internal Medicine, Hiroshima University School of Medicine.
Insights
This study identifies a family with adult-onset complete atrioventricular block (FCAVB). The condition, characterized by heart rhythm abnormalities, appears to be inherited and impacts multiple generations.
Area of Science:
- Cardiology
- Genetics
- Electrophysiology
Background:
- A family history of heart rhythm disorders, including sudden death and bradycardia, was noted.
- Acquired heart diseases were absent in the affected family members, suggesting a genetic etiology.
- Several family members presented with varying degrees of atrioventricular block and sinus node dysfunction.
Abstract:
A family of complete atrioventricular block (FCAVB) of adult onset was reported. A 36-year-old-female had 1 degree AH block, atrial and ventricular premature beats and mild sinus node dysfunction. Her father had complete AV block and died of it. A 57-year-old uncle and a 52 years-old uncle had bradycardia from 44, 5 years of age and 51 years of age, respectively, and their ECG showed complete AV block with narrow QRS waves. They were implanted with permanent pacemakers. Her grandmother died a sudden death of Adams-Stokes attack. Acquired heart diseases were not seen in any of the family Thus, this family was thought a FCAVB of adult onset.