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Related Concept Videos

Teratogenicity01:07

Teratogenicity

The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
Cancer Therapies02:49

Cancer Therapies

Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
mTOR Signaling and Cancer Progression03:03

mTOR Signaling and Cancer Progression

The mammalian target of rapamycin or mTOR protein was discovered in 1994 due to its direct interaction with rapamycin. The protein gets its name from a yeast homolog called TOR. The mTOR protein complex in mammalian cells plays a major role in balancing anabolic processes such as the synthesis of proteins, lipids, and nucleotides and catabolic processes, such as autophagy in response to environmental cues, such as availability of nutrients and growth factors.
The mTOR pathway or the...
Cancer-Critical Genes I: Proto-oncogenes01:33

Cancer-Critical Genes I: Proto-oncogenes

Genes usually encode proteins necessary for the proper functioning of a healthy cell. Mutations can often cause changes to the gene expression pattern, thereby altering the phenotype.
When the function of certain critical genes, especially those involved in cell cycle regulation and cell growth signaling cascades, gets disrupted, it upsets the cell cycle progression. Such cells with unchecked cell cycles start proliferating uncontrollably and eventually develop into tumors.
Such genes that act...
Cancer-Critical Genes II: Tumor Suppressor Genes01:05

Cancer-Critical Genes II: Tumor Suppressor Genes

Genes usually encode proteins necessary for the proper functioning of a healthy cell. Mutations can often cause changes to the gene expression pattern, thereby altering the phenotype.
When the function of certain critical genes, especially those involved in cell cycle regulation and cell growth signaling cascades, gets disrupted, it upsets the cell cycle progression. Such cells with unchecked cell cycles start proliferating uncontrollably and eventually develop into tumors.
Such genes that act...
Cancer Prevention02:59

Cancer Prevention

Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...

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Related Experiment Video

Updated: May 22, 2026

Detecting Anastasis In Vivo by CaspaseTracker Biosensor
20:16

Detecting Anastasis In Vivo by CaspaseTracker Biosensor

Published on: February 1, 2018

[Pregnancy and oncological diseases].

S Ivanov

    Akusherstvo I Ginekologiia
    |May 29, 2012
    PubMed
    Summary

    Cancer in pregnancy is rare but increasing. Treatment options like surgery and chemotherapy are safe after the first trimester, balancing maternal health with fetal development.

    Area of Science:

    • Obstetrics and Gynecology
    • Gynecologic Oncology
    • Maternal-Fetal Medicine

    Context:

    • Oncological diseases during pregnancy present unique challenges due to risks to the fetus from diagnostic procedures and treatments.
    • The incidence of cancer in pregnancy is rising, necessitating careful management strategies.

    Purpose:

    • To assess and research domestic and international experiences in diagnosing and treating oncological diseases during pregnancy.
    • To evaluate the safety and efficacy of various treatment modalities in pregnant patients.

    Summary:

    • A retrospective study analyzed 180 patients with gynecologic cancers (vulva, cervix, ovary, breast) and pregnancy over 10 years.
    • Treatment decisions for cervical cancer depend on stage, gestational age, and patient preference, with options including conservative management, radical hysterectomy, and chemo-radiotherapy.

    Related Experiment Videos

    Last Updated: May 22, 2026

    Detecting Anastasis In Vivo by CaspaseTracker Biosensor
    20:16

    Detecting Anastasis In Vivo by CaspaseTracker Biosensor

    Published on: February 1, 2018

  • Surgical intervention for adnexal masses is recommended in the second trimester, while chemotherapy for early-stage ovarian cancers may be deferred post-delivery.
  • Impact:

    • Oncological treatments, including surgery, chemotherapy, and radiotherapy (excluding pelvic/abdominal), can be safely administered after the first trimester of pregnancy.
    • The study offers two treatment algorithms for precancer and cancer of the uterine cervix and other gynecologic cancers in pregnancy.
    • Timely treatment of pregnant patients with oncological diseases is crucial, emphasizing a balance between maternal care and fetal well-being.