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Updated: May 22, 2026

Innovative Adipose Tissue Fractionation for Transforming Fat into Specialized Components
Published on: July 11, 2025
Body contouring: the skinny on noninvasive fat removal
1Laser and Cosmetic Center and Wellman Center for Photomedicine, Massachusetts General Hospital, Boston, MA 02114, USA.
Abstract:
Historically, the approach to body contouring has largely involved invasive procedures, such as liposuction. Recently, several new devices for noninvasive fat removal have received clearance by the Food and Drug Administration for the treatment of focal adiposity. Modalities are aimed primarily at targeting the physical properties of fat that differentiate it from the overlying epidermis and dermis, thus selectively resulting in removal. This review will focus on 3 novel approaches to noninvasive selective destruction of fat.

