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Updated: May 21, 2026

Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates
Published on: September 5, 2017
[The natural story of tuberculosis]
Hélène Leroy1, Matthieu Revest, Pierre Tattevin
1Maladies infectieuses et réanimation médicale, CHU Pontchaillou.
Abstract:
Tuberculosis is one of the infectious diseases that had a huge impact on the health of the populations since the XVIIth century, and this remains true for most of the people in the World in 2012. Its natural story involves: contamination (inhalation of infectious particles, the Pflügge droplets, originating from a patient with bacillary tuberculosis); primary infection (remarkable by initial unresponsiveness of the immune system, followed by strong cellular immunity development within 3 to 9 weeks); latent tuberculosis infection, non-contagious and totally asymptomatic, with efficient control of tuberculosis bacilli replication, lasting for life in more than 90% of cases; and less frequently, tuberculosis disease in patients with insufficient immunity, including children less than 5 years, immunocompromised, and patients recently infected.
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