Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Role of Cerebellum and Prefrontal Cortex in Memory01:14

Role of Cerebellum and Prefrontal Cortex in Memory

The cerebellum, while traditionally associated with motor control, also plays a crucial role in memory, particularly in procedural memory, which involves learning motor tasks that become automatic through repetition. For example, studies have shown that when the cerebellum is damaged, individuals or animals lose the ability to learn conditioned motor responses, such as the conditioned eye-blink response in classical conditioning experiments with rabbits. This study demonstrates the cerebellum's...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Accelerometer-derived movement phenotypes and adolescent mental health in pediatric obesity: A causal machine-learning study.

International journal of clinical and health psychology : IJCHP·2026
Same author

Passive exercise provides a simultaneous and postexercise executive function benefit.

Frontiers in cognition·2026
Same author

Dorsomedial prefrontal cortex links abstract planning to motor execution.

Communications biology·2026
Same author

Pedal cadence differentially impacts cerebral blood flow but not a postexercise executive function benefit: evidence from active and passive exercise.

Journal of neurophysiology·2026
Same author

Feasibility and exploratory cognitive outcomes of three exercise modalities in oldest-old adults in assisted living facilities: A 24-week pilot randomized controlled trial.

Journal of affective disorders·2026
Same author

Timing of MVPA and psychosocial outcomes in adolescents with overweight/obesity.

International journal of clinical and health psychology : IJCHP·2026

Related Experiment Video

Updated: May 21, 2026

Assessing Corticospinal Excitability During Goal-Directed Reaching Behavior
05:05

Assessing Corticospinal Excitability During Goal-Directed Reaching Behavior

Published on: December 2, 2022

Reduced cortical motor potentials underlie reductions in memory-guided reaching performance.

Olav Krigolson1, Jon Bell, Courtney M Kent

  • 1Department of Psychology and Neuroscience, Dalhousie University, Halifax, Nova Scotia, Canada.

Motor Control
|May 31, 2012
PubMed
Summary

This study reveals distinct neural processing for visually versus memory-guided reaches. Memory-guided movements show altered brain activity, challenging theories about real-time planning.

More Related Videos

Investigating Motor Skill Learning Processes with a Robotic Manipulandum
07:52

Investigating Motor Skill Learning Processes with a Robotic Manipulandum

Published on: February 12, 2017

Measuring and Manipulating Functionally Specific Neural Pathways in the Human Motor System with Transcranial Magnetic Stimulation
09:52

Measuring and Manipulating Functionally Specific Neural Pathways in the Human Motor System with Transcranial Magnetic Stimulation

Published on: February 23, 2020

Related Experiment Videos

Last Updated: May 21, 2026

Assessing Corticospinal Excitability During Goal-Directed Reaching Behavior
05:05

Assessing Corticospinal Excitability During Goal-Directed Reaching Behavior

Published on: December 2, 2022

Investigating Motor Skill Learning Processes with a Robotic Manipulandum
07:52

Investigating Motor Skill Learning Processes with a Robotic Manipulandum

Published on: February 12, 2017

Measuring and Manipulating Functionally Specific Neural Pathways in the Human Motor System with Transcranial Magnetic Stimulation
09:52

Measuring and Manipulating Functionally Specific Neural Pathways in the Human Motor System with Transcranial Magnetic Stimulation

Published on: February 23, 2020

Area of Science:

  • Neuroscience
  • Motor Control
  • Cognitive Psychology

Background:

  • Visually-guided reaches rely on real-time visual feedback.
  • Memory-guided reaches are executed without direct visual guidance.
  • Previous research indicates behavioral differences in reach accuracy.

Purpose of the Study:

  • To investigate neural processing differences between visually and memory-guided reaches using event-related potentials (ERPs).
  • To compare brain activity patterns during the planning and execution phases of both reach types.
  • To evaluate the timing of motor plan generation for memory-guided movements.

Main Methods:

  • Utilized event-related potential (ERP) methodology.
  • Recorded neural activity during visually and memory-guided reaching tasks.
  • Analyzed brain potentials over medial-frontal cortex in relation to movement kinematics.

Main Results:

  • Memory-guided reaches showed greater undershooting of target locations compared to visually-guided reaches.
  • Reduced medial-frontal cortical potentials were observed during target presentation and post-movement onset for memory-guided reaches.
  • The amplitude of medial-frontal potentials correlated with movement acceleration and deceleration for both reach types.

Conclusions:

  • Memory-guided reaches appear to be planned based on a motor plan generated when the target is visible and stored for later use.
  • These findings contradict theories suggesting memory-guided reaches are planned immediately before movement onset.
  • The study highlights the role of pre-generated motor plans in memory-guided actions and their neural underpinnings.