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Related Concept Videos

Degenerative Disc Disease ll: Pathophysiology01:23

Degenerative Disc Disease ll: Pathophysiology

The symptoms of degenerative disc disease arise from a combination of mechanical compression, vascular compromise, and biochemical inflammation, which together disrupt nerve function and produce pain.Mechanical CompressionDisc degeneration reduces height and elasticity, predisposing to herniation of the nucleus pulposus, a major cause of radicular pain. Herniations may be protrusion (bulging with intact annulus), extrusion (nucleus extends beyond disc but remains connected), or sequestration...
Herniated Intervertebral Disc l: Introduction01:29

Herniated Intervertebral Disc l: Introduction

Intervertebral disc herniation refers to the displacement of the nucleus pulposus (the gel-like inner core of the disc) through a tear or weakened area in the annulus fibrosus (the outer fibrous ring). The displaced disc material extends beyond the normal boundaries of the disc space and may compress or irritate nearby spinal nerve roots or, less commonly, the spinal cord.Etiology and Risk FactorsHerniation commonly results from degeneration, in which aging reduces disc hydration and...
Degenerative Disc Disease I: Introduction01:27

Degenerative Disc Disease I: Introduction

Degenerative disc disease is a chronic condition in which intervertebral discs gradually lose structure and function. It is not infectious or autoimmune; rather, it results from age-related biochemical and mechanical changes, influenced by genetic, metabolic, and environmental factors.Structure and Function of DiscsThe spine contains 23 intervertebral discs that absorb load, distribute forces, maintain spacing, and allow flexibility. Each disc consists of a nucleus pulposus, a gel-like core...

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Related Experiment Video

Updated: May 21, 2026

Transtubular Endoscopic Posterolateral Decompression for L5-S1 Lumbar Lateral Disc Herniation
10:09

Transtubular Endoscopic Posterolateral Decompression for L5-S1 Lumbar Lateral Disc Herniation

Published on: October 14, 2022

Lumbar diskogenic pain, provocation diskography, and imaging correlates.

Timothy P Maus1, Charles N Aprill

  • 1Department of Radiology, Mayo Medical School, Rochester, MN 55905, USA. timpmaus@gmail.com

Radiologic Clinics of North America
|May 31, 2012
PubMed
Summary
This summary is machine-generated.

Diskogenic pain, originating from the intervertebral disc, is diagnosed using provocation diskography. This review examines its use in diagnosing lumbar diskogenic pain and explores imaging predictors.

Related Experiment Videos

Last Updated: May 21, 2026

Transtubular Endoscopic Posterolateral Decompression for L5-S1 Lumbar Lateral Disc Herniation
10:09

Transtubular Endoscopic Posterolateral Decompression for L5-S1 Lumbar Lateral Disc Herniation

Published on: October 14, 2022

Area of Science:

  • Orthopedics
  • Pain Medicine
  • Radiology

Background:

  • Diskogenic pain originates from the intervertebral disc's innervation, causing axial pain without radicular symptoms.
  • No definitive pathoanatomic gold standard exists; histological examination cannot identify a painful disc.
  • Provocation diskography is the current reference standard for diagnosing diskogenic pain.

Purpose of the Study:

  • To review diskogenic pain and the history and current use of provocation diskography.
  • To examine imaging features that may predict a positive diskogram for non-invasive diagnosis.

Main Methods:

  • Review of extensive literature on diskogenic pain and provocation diskography.
  • Examination of imaging features associated with positive diskograms.
  • Analysis of the diagnostic utility of provocation diskography for lumbar pain.

Main Results:

  • Provocation diskography remains the reference standard for diskogenic pain diagnosis.
  • Literature suggests imaging features may predict positive diskograms.
  • Non-invasive diagnosis of diskogenic pain through imaging is an area of ongoing research.

Conclusions:

  • Diskogenic pain diagnosis relies on provocation diskography.
  • Further research into imaging predictors could enable non-invasive diagnosis.
  • Understanding imaging features is crucial for managing axial back pain.