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Updated: May 21, 2026

Split Hybridization Probe Utilizing a DNA Fluorescent Light-up Aptamer as a Signal Reporter for Sequence-Specific Nucleic Acid Analysis
Published on: July 8, 2025
A fluorescent turn-on probe for bisulfite based on hydrogen bond-inhibited C=N isomerization mechanism
Yuan-Qiang Sun1, Pi Wang, Jing Liu
1School of Chemistry and Chemical Engineering, Shanxi University, Taiyuan 030006, China.
Abstract:
A fluorescence turn-on probe for bisulfite has been developed by taking advantage of the specific reaction of bisulfite and aldehyde in combination with the hydrogen bond inhibited C=N isomerization mechanism. The practical value of this selective and sensitive fluorescent probe was confirmed by its application to detection of bisulfite in granulated sugar.
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