Related Experiment Video
Updated: May 21, 2026

A Computerized Test Battery to Study Pharmacodynamic Effects on the Central Nervous System of Cholinergic Drugs in Early Phase Drug Development
Published on: February 11, 2019
Pharmacological dosage concepts: how useful are they for educators and speech-language pathologists?
Abstract:
The first part of this response to Baker (2012) examines studies that have attempted to determine the optimum treatment intensity of reading interventions associated with a Response to Intervention (RTI) model of service delivery. In general, the findings indicated that differences in broad measures of intensity (duration and scheduling) did not result in differences in reading outcomes. These non-significant findings and Baker's excellent discussion of all of the factors that impact treatment outcomes led me to question how useful pharmacological dosage concepts are for educators and speech-language pathologists (SLPs). This commentary concludes by acknowledging that the more information available about the active ingredients of treatment episodes, the better able one will be to design effective and efficient interventions to improve speech, language, and literacy.
Related Concept Videos
Dosage Regimens: Partial Pharmacokinetic Parameters
Dosage Regimens: Designs and Approaches
Determination of Multiple Dosing Parameters: Loading and Maintenance Doses
Dosage Regimen Designs: Nomograms and Tabulations
Dosage Regimen: Individualization
Dose Size and Dosing Frequency: Determination Methods

