Automatic seizure detection in SEEG using high frequency activities in wavelet domain.
L Ayoubian1, H Lacoma, J Gotman
1Montreal Neurological Institute and Hospital, McGill University, Montreal, Quebec, Canada. leilayou_54@yahoo.com
Medical Engineering & Physics
|June 1, 2012
Summary
This study introduces a novel seizure detection system using high-frequency electroencephalography (EEG) activity. The system shows potential for clinical use by detecting epileptic seizures with significant high-frequency contributions.
Area of Science:
- Neurology
- Biomedical Engineering
- Signal Processing
Background:
- Current automatic seizure detection methods have limitations in specificity and speed.
- High-frequency (80-500 Hz) activity in intracranial EEG is prominent in epilepsy but underutilized for detection.
Purpose of the Study:
- To evaluate the contribution of high-frequency EEG activity to epileptic seizure detection.
- To develop and assess a novel seizure detection system incorporating these frequencies.
Main Methods:
- Utilized 30 hours of intracranial EEG data from 15 patients with 15 seizures for training.
- Employed wavelet decomposition, feature extraction, adaptive thresholding, and artifact removal.
- Developed an EMG removal algorithm based on frequency band correlation and energy spread.
Main Results:
- Tested on 36 hours of intracranial EEG data with 18 seizures.
- Achieved 72% sensitivity, 0.7 false detections per hour, and a median delay of 5.7 seconds.
- Missed seizures were associated with subtle high frequencies or EMG removal; false detections stemmed from EMG or interictal activity.
Conclusions:
- The developed system demonstrates sufficient performance for potential clinical application.
- High-frequency EEG activity can significantly enhance the detection of epileptic seizures.
- The system's performance is promising despite using frequencies typically outside routine clinical interpretation.
More Related Videos
Related Concept Videos
01:13Seizures: Classification
Epilepsy is primarily characterized by unpredictable seizures, either provoked by an identifiable factor, such as injury or illness, or unprovoked, occurring spontaneously without apparent cause.
Seizures are typically classified into two main categories: focal and generalized seizures.
Focal Seizures
Focal seizures originate from specific regions of the brain. These seizures are further sub-classified into two types:
Seizures are typically classified into two main categories: focal and generalized seizures.
Focal Seizures
Focal seizures originate from specific regions of the brain. These seizures are further sub-classified into two types:
01:20Seizures l: Introduction
Understanding seizures and epilepsy relies on key definitions that help in recognizing, classifying, and managing these disorders. These definitions provide a framework for recognizing, classifying, and managing seizure disorders.DefinitionsA seizure is a sudden, abnormal burst of electrical activity in the brain that can cause changes in awareness, movement, sensation, or behavior, depending on the area involved. Epilepsy is a chronic condition characterized by recurrent, unprovoked seizures,...
01:19Seizures ll: Types
Seizures are sudden bursts of abnormal electrical discharge in the brain that interfere with normal function. They are commonly divided into three groups: focal seizures, generalized seizures, and other types that do not fit neatly into either category.Focal SeizuresFocal seizures begin in a single brain region. When awareness is preserved, they are called focal aware seizures and may cause sensations such as tingling, unusual smells, or flashing lights. When awareness is impaired, they are...
01:24Epilepsy and Seizures: Overview
Epilepsy is a chronic neurological disease marked by recurrent, unpredictable seizures. These seizures are caused by abnormal electrical discharges in the brain, leading to behavior, sensation, or consciousness alterations. They can also cause transient impairment of awareness, interfering with daily activities.
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...