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Related Concept Videos

Taping Over Different Ground Profiles01:12

Taping Over Different Ground Profiles

Taping over varying ground profiles requires careful adaptation to achieve accurate measurements. On smooth, level ground with minimal vegetation, the tape can rest directly on the ground. Here, the taping team, typically consisting of a head and a rear tapeman, coordinates their positions with clear communication. The rear tapeman holds the tape at the starting point and guides the head tapeman toward a range pole placed beyond the endpoint, using hand or voice signals to ensure alignment.On...
Absolute and Local Extreme Values01:22

Absolute and Local Extreme Values

The highest and lowest values of a function, relative to a reference axis, are known as extreme values. These include absolute maximum and absolute minimum values, which represent the highest and lowest points the function reaches across its entire domain. Within a restricted portion of the function, the highest and lowest values are referred to as local maximum and local minimum values, respectively.Periodic functions, such as sine and cosine, show extreme values at infinitely many points due...
Tertiary Healthcare System01:21

Tertiary Healthcare System

Specialized care provided over an extended period is called tertiary care. Usually, a primary or secondary care physician will refer a patient to tertiary care. A patient's maximum physical and mental function is restored in tertiary care, which is caused due to the impact of a chronic illness or condition. Tertiary care aims to achieve the highest level of functioning possible while managing chronic illness. For example, a patient who falls and fractures their hip will need secondary care to...
Torts III01:26

Torts III

Types of Quasi-intentional Torts in Healthcare
Quasi-intentional torts in healthcare involve acts where intent is not directed to harm an individual but results in harm due to careless or reckless speech.

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Related Experiment Video

Updated: May 21, 2026

Development of Targeting Induced Local Lesions IN Genomes (TILLING) Populations in Small Grain Crops by Ethyl Methanesulfonate Mutagenesis
08:36

Development of Targeting Induced Local Lesions IN Genomes (TILLING) Populations in Small Grain Crops by Ethyl Methanesulfonate Mutagenesis

Published on: July 16, 2019

TILLING in extremis.

Trevor L Wang1, Cristobal Uauy, Fran Robson

  • 1John Innes Centre, Norwich Research Park, Norwich, UK. trevor.wang@jic.ac.uk

Plant Biotechnology Journal
|June 2, 2012
PubMed
Summary
This summary is machine-generated.

Targeting Induced Local Lesions in Genomes (TILLING) is a key non-transgenic method for crop genetic improvement. Recent advances, particularly next-generation sequencing, are making TILLING an in silico process for plant breeding.

Related Experiment Videos

Last Updated: May 21, 2026

Development of Targeting Induced Local Lesions IN Genomes (TILLING) Populations in Small Grain Crops by Ethyl Methanesulfonate Mutagenesis
08:36

Development of Targeting Induced Local Lesions IN Genomes (TILLING) Populations in Small Grain Crops by Ethyl Methanesulfonate Mutagenesis

Published on: July 16, 2019

Area of Science:

  • Genetics
  • Genomics
  • Plant Science

Background:

  • Targeting Induced Local Lesions in Genomes (TILLING) is a crucial reverse genetics technique in plants.
  • It is a dominant non-transgenic method for generating mutations in specific genes.

Observation:

  • TILLING has evolved significantly over the past decade.
  • The integration of next-generation sequencing (NGS) allows for multiplexing of gene targets and genomes.

Findings:

  • NGS is transforming TILLING into a computational (in silico) procedure.
  • Recent developments address challenges in polyploid and vegetatively propagated crops.

Implications:

  • TILLING advancements, driven by NGS, will accelerate crop improvement and breeding strategies.
  • The evolution towards in silico TILLING promises greater efficiency and broader applicability in plant genetics research.