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Updated: May 21, 2026

Three-Dimensional Cell Culture Models to Investigate the Epithelial Barrier in Eosinophilic Esophagitis
Published on: May 10, 2024
[Eosinophilic gastroenteritis]
N Maàmouri1, S Guellouz, N Belkahla
1Service de gastroentérologie B, hôpital La Rabta, 1007 Tunis Jebbari, Tunisia. nadiamaamouri1939@yahoo.fr
Eosinophilic gastroenteritis, a rare gastrointestinal disorder, often presents with abdominal pain and vomiting. Prompt diagnosis via histology or ascites analysis and treatment with oral prednisolone can lead to symptom resolution.
Area of Science:
- Gastroenterology
- Immunology
- Pathology
Background:
- Eosinophilic gastroenteritis is a rare condition with variable gastrointestinal symptoms.
- It involves eosinophilic infiltration of the GI tract, commonly affecting the stomach and proximal small bowel.
Observation:
- A retrospective review identified eight adult cases of eosinophilic gastroenteritis between 1990 and 2010.
- Common symptoms included abdominal pain, vomiting, weight loss, and ascites, with 87.5% exhibiting hypereosinophilia.
Findings:
- Subserosal involvement was noted in seven patients, and mucosal in one.
- Treatment with oral prednisolone led to symptom resolution within one month in four patients; the remaining four improved spontaneously.
Implications:
- Eosinophilic gastroenteritis should be considered in patients with GI discomfort and peripheral eosinophilia.
- Histological confirmation of eosinophilic infiltration or high eosinophilic ascites is crucial for diagnosis.
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