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One-pot synthesized DNA-CdTe quantum dots applied in a biosensor for the detection of sequence-specific

Cuiling Zhang1, Jing Xu, Shiming Zhang

  • 1Key Laboratory of Analytical Chemistry for Biology and Medicine (Ministry of Education), College of Chemistry and Molecular Sciences, Wuhan University, Wuhan 430072, PR China.

Chemistry (Weinheim an Der Bergstrasse, Germany)
|June 2, 2012
PubMed
Abstract

No abstract available in PubMed .

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DNA probes are fragments of DNA labeled with a reporter tag to enable their detection or purification. The resulting labeled DNA probes can then hybridize to target nucleic acid sequences through complementary base-pairing, and may be used to recover or identify these regions.
Radioisotopes, fluorophores, or small molecule binding partners like biotin or digoxigenin, are the most widely used reporter tags for labeling DNA probes. These labels can be attached to the probe DNA molecule via...

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