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Updated: May 21, 2026

Y-90 Radioembolization and PD-1 Inhibitor as Neoadjuvant Treatment in Hepatocellular Carcinoma
Published on: May 24, 2024
Hepatic radioembolization complicated by fulminant hepatic failure
1Department of Radiology - Feinberg School of Medicine, Northwestern University, Chicago, Illinois.
Abstract:
A 68-year-old man with a history of metastatic colorectal carcinoma underwent left hepatic lobectomy and right hepatic wedge resection as initial treatment of his metastatic disease. He subsequently underwent right lobar radioembolization for treatment of a segment 8 lesion. At 6 weeks postembolization, he developed hepatic dysfunction which rapidly progressed to fulminant liver failure. A liver biopsy revealed hepatic venous obstruction and fibrosis. The patient died 14 weeks after radioembolization.
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