Clinico-Microbiological Aspects of Necrotising Fasciitis in Type II Diabetes Mellitus

Asayas Bosco Chandra Kumar1, S G Subramanyam, Arun B Kilpadi

  • 1St. John's national academy of health sciences, Sarjapur road, Bangalore, 605034 India.

Insights

Necrotising fasciitis in diabetic patients requires high suspicion for early diagnosis. Aggressive surgical debridement and broad-spectrum antibiotics are crucial for favorable outcomes and reduced mortality.

Area of Science:

  • Infectious Diseases
  • Diabetology
  • Surgical Pathology

Background:

  • Necrotising fasciitis is a severe soft tissue infection with high morbidity, particularly in immunocompromised individuals.
  • Diabetic patients are at increased risk due to impaired immunity and potential for delayed diagnosis.
  • Early detection and management are critical for improving patient outcomes.

Purpose of the Study:

  • To determine the clinical presentation and causative organisms of necrotising fasciitis in type II diabetic patients.
  • To evaluate the effectiveness of early surgical intervention and antibiotic therapy.
  • To compare the study's mortality rate with existing literature.

Main Methods:

  • A prospective descriptive study of 62 type II diabetic patients with necrotising fasciitis over three years.
  • Data collection included patient history, physical examination, microbial culture and sensitivity, and chart reviews.
  • Wagner's score was utilized as a diagnostic and prognostic tool.

Main Results:

  • The most common presentation was a necrotic skin patch with cellulitis.
  • Beta-hemolytic streptococci and E. coli were the predominant organisms identified.
  • Average hospital stay was 13.74 days, with a mean delay in presentation of 6 days.
  • Wagner's score aided diagnosis, and poor foot care correlated with extensive lesions.
  • The mortality rate in the study group was 1.6%.

Conclusions:

  • High clinical suspicion is essential for necrotising fasciitis in diabetic patients with acutely swollen limbs.
  • Prompt surgical debridement and broad-spectrum antibiotics are mandatory for favorable outcomes.
  • Comprehensive foot care is vital for preventing severe lesions in diabetic patients.
  • Wagner's scoring can help predict the need for repeat surgeries.
  • Effective management strategies can help contain the mortality rate of necrotising fasciitis in type II diabetes mellitus.

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