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Clinico-Microbiological Aspects of Necrotising Fasciitis in Type II Diabetes Mellitus
Asayas Bosco Chandra Kumar1, S G Subramanyam, Arun B Kilpadi
1St. John's national academy of health sciences, Sarjapur road, Bangalore, 605034 India.
Abstract:
Necrotising fasciitis is insidiously advancing soft tissue infection, characterized by widespread fascial necrosis. One of the most common conditions encountered in the clinical practice and which required clinical suspicion in patients who have less resistance to these infections. Especially in diabetic patients who are more prone for such infection due to low immunity and other reasons like early detection of these infections helps these patients to have a better recovery by aggressive surgical management and other measures required for the same. Literature has enough evidence on how serious this entity. Hence this study is designed in that aspect to help in early diagnosis and appropriate treatment. This study will help to determine the clinical presentation, the polymicrobial involved. The organisms most closely linked to necrotizing fasciitis are group A beta-hemolytic streptococci, although the disease may also be caused by other bacteria and their sensitivity patterns will help us to install appropriate antibiotics with the surgical management. And to compare our mortality rate with the other studies. A prospective descriptive study including all type II diabetic patients with necrotizing fasciitis over 3 years. Patients were evaluated in detail with respect to patient's history, examination, culture sensitivity and chart reviews and followed up using standard evaluation tools to measure the various outcomes. In 62 patients, the commonest clinical presentation was necrotic patch of skin and cellulites. The organisms cultured being beta hemolytic streptococci and E.Coli. The culture sensitivity pattern is to broad-spectrum antibiotics. The average stay in the hospital was about 13.74 days for the study group and the time delay in presentation is 6 days. Wagner's score is a useful tool for aiding the diagnosis. Patients without foot care had extensive lesions. And a mortality rate of 1.6 % in these patients. In an acutely swollen limb in a diabetic patient a high degree of suspicion of necrotizing fasciitis is required. A detailed foot care is warranted in these patients. An early extensive debridement is mandatory and key for a favorable outcome. And to start on broad- spectrum antibiotics is advisable. Wagner's scoring is helpful to predict the chances of a second surgery. With the above entities in mind the mortality rate of necrotizing fasciitis in type ii diabetes mellitus can be contained.
Insights
Necrotising fasciitis in diabetic patients requires high suspicion for early diagnosis. Aggressive surgical debridement and broad-spectrum antibiotics are crucial for favorable outcomes and reduced mortality.
Area of Science:
- Infectious Diseases
- Diabetology
- Surgical Pathology
Background:
- Necrotising fasciitis is a severe soft tissue infection with high morbidity, particularly in immunocompromised individuals.
- Diabetic patients are at increased risk due to impaired immunity and potential for delayed diagnosis.
- Early detection and management are critical for improving patient outcomes.
Purpose of the Study:
- To determine the clinical presentation and causative organisms of necrotising fasciitis in type II diabetic patients.
- To evaluate the effectiveness of early surgical intervention and antibiotic therapy.
- To compare the study's mortality rate with existing literature.
Main Methods:
- A prospective descriptive study of 62 type II diabetic patients with necrotising fasciitis over three years.
- Data collection included patient history, physical examination, microbial culture and sensitivity, and chart reviews.
- Wagner's score was utilized as a diagnostic and prognostic tool.
Main Results:
- The most common presentation was a necrotic skin patch with cellulitis.
- Beta-hemolytic streptococci and E. coli were the predominant organisms identified.
- Average hospital stay was 13.74 days, with a mean delay in presentation of 6 days.
- Wagner's score aided diagnosis, and poor foot care correlated with extensive lesions.
- The mortality rate in the study group was 1.6%.
Conclusions:
- High clinical suspicion is essential for necrotising fasciitis in diabetic patients with acutely swollen limbs.
- Prompt surgical debridement and broad-spectrum antibiotics are mandatory for favorable outcomes.
- Comprehensive foot care is vital for preventing severe lesions in diabetic patients.
- Wagner's scoring can help predict the need for repeat surgeries.
- Effective management strategies can help contain the mortality rate of necrotising fasciitis in type II diabetes mellitus.
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