A case of L-tryptophan-induced eosinophilia-myalgia resulting in death

A syndrome of eosinophilia and myalgias associated with the ingestion of L-tryptophan has recently been described. In a large majority of the cases reported to the Centers for Disease Control thus far, discontinuation of L-tryptophan consumption has resulted in complete resolution of symptoms. The author presents a case of L-tryptophan-induced eosinophilia-myalgia syndrome which was progressive despite discontinuation of the L-tryptophan. The condition was refractory to treatment and ultimately resulted in the death of the patient.