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Updated: May 21, 2026
11:56
In Vitro Bioluminescence Assay to Characterize Circadian Rhythm in Mammary Epithelial Cells
Published on: September 28, 2017
Advances in understanding the peripheral circadian clocks.
Jacob Richards1, Michelle L Gumz
1Department of Medicine, University of Florida, Gainesville, Florida, USA.
Summary
The body
Area of Science:
- Physiology
- Chronobiology
Background:
- The circadian clock system regulates physiological processes.
- It comprises a central clock (suprachiasmatic nucleus) and peripheral clocks in tissues.
Purpose of the Study:
- To introduce and overview peripheral clocks.
- To discuss their mechanisms, targets, and disease implications.
Main Methods:
- This is a review article.
- It synthesizes existing knowledge on peripheral clocks.
Main Results:
- Peripheral clocks are integral to tissue-specific gene expression.
- They influence cardiovascular, metabolic, endocrine, immune, and reproductive systems.
Conclusions:
- Peripheral clocks are crucial for diverse physiological functions.
- Understanding them offers insights into disease states.
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