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An Integrated Approach for Microprotein Identification and Sequence Analysis
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Published on: July 12, 2022

ExPASy: SIB bioinformatics resource portal.

Panu Artimo1, Manohar Jonnalagedda, Konstantin Arnold

  • 1Vital-IT Group, SIB Swiss Institute of Bioinformatics, Lausanne, Switzerland.

Nucleic Acids Research
|June 5, 2012
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Summary

ExPASy has evolved into an integrated bioinformatics portal, offering seamless access to diverse life science resources. This enhanced platform serves both expert and novice users across various scientific domains.

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Area of Science:

  • Bioinformatics
  • Life Sciences
  • Proteomics
  • Genomics

Background:

  • ExPASy is a renowned bioinformatics resource.
  • It traditionally focused on proteomics.
  • The need for an integrated platform across life sciences was identified.

Purpose of the Study:

  • To describe the evolution of ExPASy into an extensible and integrative portal.
  • To highlight the expanded access to diverse scientific resources.
  • To cater to both expert and novice users in life sciences.

Main Methods:

  • Development of a single web portal as a common entry point.
  • Integration of decentralized resources (databases, software tools) from SIB Swiss Institute of Bioinformatics and partners.
  • Implementation of a cross-resource search function.
  • Monitoring of resource availability and usage.

Main Results:

  • ExPASy now provides seamless access to a wide range of resources in proteomics, genomics, and other life science domains.
  • The portal integrates resources hosted by different SIB groups and external institutions.
  • A search function across selected resources is available.
  • New visual guidance aids newcomers to the platform.

Conclusions:

  • The enhanced ExPASy portal offers a unified access point to a broad spectrum of life science tools and data.
  • It effectively serves a diverse user base, from specialists to beginners.
  • The platform represents a significant advancement in bioinformatics resource accessibility and integration.