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Related Concept Videos

Brain Imaging01:14

Brain Imaging

Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans),  magnetic resonance imaging (MRI),  functional magnetic resonance imaging (fMRI), and Transcranial Magnetic Stimulation (TMS).

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Related Experiment Video

Updated: May 21, 2026

Probing the Brain in Autism Using fMRI and Diffusion Tensor Imaging
12:21

Probing the Brain in Autism Using fMRI and Diffusion Tensor Imaging

Published on: September 12, 2011

Functional MRI studies in disruptive behaviour disorders.

M Bellani1, M Garzitto, P Brambilla

  • 1Section of Psychiatry and Clinical Psychology, Department of Public Health and Community Medicine, Inter-University Center for Behavioural Neurosciences (ICBN), University of Verona, Verona, Italy. marcella.bellani@univr.it

Epidemiology and Psychiatric Sciences
|June 8, 2012
PubMed
Summary
This summary is machine-generated.

Disruptive behaviour disorders (DBDs) involve aggression and rule-breaking. Functional magnetic resonance imaging studies suggest neural dysfunctions in brain regions processing emotions in individuals with DBDs.

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Area of Science:

  • Neuroscience
  • Developmental Psychology
  • Psychiatry

Background:

  • Disruptive Behaviour Disorders (DBDs), including conduct disorder and oppositional defiant disorder, are characterized by aggression and antisocial behaviors violating social norms.
  • DBDs are developmental conditions with significant implications for individuals and society.
  • Understanding the biological basis of DBDs is crucial for developing effective interventions.

Purpose of the Study:

  • To review and synthesize findings from functional magnetic resonance imaging (fMRI) studies investigating the neural underpinnings of Disruptive Behaviour Disorders.
  • To identify brain regions and networks implicated in the pathophysiology of DBDs.
  • To highlight the role of affective processing in the neurobiology of DBDs.

Main Methods:

  • Systematic review and synthesis of published functional magnetic resonance imaging (fMRI) studies focusing on individuals diagnosed with Disruptive Behaviour Disorders.
  • Analysis of brain activity patterns during tasks involving affective stimuli.
  • Examination of structural and functional connectivity in relevant neural circuits.

Main Results:

  • fMRI studies indicate significant neural dysfunctions in individuals with DBDs when processing affective stimuli.
  • Specific alterations are observed in the medial and orbitofrontal prefrontal cortex, key areas for emotional regulation and decision-making.
  • Dysfunctions extend to subcortical structures connected to these prefrontal regions, suggesting broader network involvement.

Conclusions:

  • Evidence from fMRI studies points to distinct neural correlates of Disruptive Behaviour Disorders.
  • Impaired processing of affective information in specific prefrontal and subcortical brain regions is a key finding.
  • These neurobiological insights provide a foundation for future research and targeted therapeutic strategies for DBDs.