RECOVER evidence and knowledge gap analysis on veterinary CPR. Part 6: Post-cardiac arrest care

Area of Science:

• Veterinary Medicine
• Critical Care
• Cardiopulmonary Resuscitation

Background:

• Return of spontaneous circulation (ROSC) is a critical juncture in cardiopulmonary resuscitation (CPR).
• Evidence-based interventions following ROSC are crucial for improving patient outcomes in veterinary medicine.
• Significant knowledge gaps exist regarding optimal post-ROSC care in animals.

Purpose of the Study:

• To systematically review evidence for interventions after ROSC in veterinary CPR.
• To identify critical knowledge gaps in post-cardiac arrest care for animals.
• To develop consensus-based recommendations for clinical application.

Main Methods:

• Systematic literature evaluation and evidence grading.
• Categorization of research articles by evidence level and quality.
• Development of consensus on post-cardiac arrest care concepts.

Main Results:

• Fifteen key clinical questions for post-ROSC care were addressed.
• Most research involved non-canine species or experimental models.
• Outcome metrics varied widely, from mechanistic endpoints to survival and neurological function.

Conclusions:

• Statements were formulated for supportive (e.g., therapeutic hypothermia) and neutral (e.g., seizure prophylaxis) post-ROSC treatments.
• Evidence grading enhanced transparency of recommendations.
• Identified knowledge gaps provide a roadmap for future veterinary research in post-cardiac arrest care.