Preeclampsia, placenta, oxidative stress, and PMCA.

Cilia Abad1, Teresa Proverbio, Sandy Piñero

  • 1Laboratorio de Bioenergética Celular, Centro de Biofísica y Bioquímica, Instituto Venezolano de Investigaciones Científicas, Caracas, Venezuela.

Summary

Preeclampsia is linked to increased oxidative stress and reduced plasma membrane Ca-ATPase (PMCA) activity in placental and red blood cell membranes. This dysfunction may stem from lipid peroxidation by-products affecting cell membrane integrity.

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