Related Experiment Video
Updated: May 21, 2026

Fluorescence-mediated Tomography for the Detection and Quantification of Macrophage-related Murine Intestinal Inflammation
Published on: December 15, 2017
A new look at Crohn's disease: novel imaging techniques
Mahmoud Al-Hawary1, Ellen M Zimmermann
1Abdominal Division, Department of Radiology, University of Michigan Medical Center, Ann Arbor, Michigan 49109, USA.
Recent advances in gut imaging, including CT enterography (CTE) and magnetic resonance enterography (MRE), are revolutionizing Crohn
Area of Science:
- Gastroenterology and Radiology
- Inflammatory Bowel Disease Diagnostics
- Medical Imaging Technologies
Background:
- Gut imaging is crucial for assessing Crohn's disease activity, complications, and symptoms.
- Technological advancements in imaging offer novel insights into patient management and outcomes.
- The field of Crohn's disease imaging is rapidly evolving with new applications.
Purpose of the Study:
- To review recent advancements in imaging techniques for Crohn's disease assessment.
- To highlight the current status and future potential of various imaging modalities.
Main Methods:
- Review of key literature on cross-sectional imaging techniques published in the past year.
- Focus on computed tomography (CT) enterography (CTE), magnetic resonance enterography (MRE), transcutaneous ultrasound, and PET-based imaging.
- Inclusion of advanced MRI sequences such as diffusion-weighted imaging (DWI) and magnetization transfer imaging (MTI).
Main Results:
- CTE and MRE are established as standard imaging modalities for small bowel Crohn's disease.
- PET scanning shows promise but is primarily utilized in research settings.
- Transcutaneous ultrasound is emerging as a cost-effective, radiation-free alternative.
- New MRI sequences provide valuable insights into disease monitoring.
Conclusions:
- CT enterography and magnetic resonance enterography represent the current standard for small bowel Crohn's disease imaging.
- Emerging techniques like ultrasound and advanced MRI sequences hold significant promise for future clinical practice.
- Continued research in PET imaging may expand its routine application in Crohn's disease management.
Related Concept Videos
Inflammatory Bowel Disease III: Crohn's Disease
Inflammatory Bowel Disease II: Crohn's Disease
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by transmural...
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the colonic...
Imaging Studies III: Gastrointestinal Motility Studies and Virtual Colonoscopy
Radionuclide Testing
Radionuclide testing is a sophisticated medical technique for assessing gastrointestinal motility. It focuses on gastric emptying and colonic transit time. Radioactive markers track the movement of food through the digestive system, providing insights into gastrointestinal disorders.
In gastric emptying studies, a meal's liquid and solid...
Drugs for Treatment of Crohn's Disease in IBD Using Immunomodulatory Agents
Inflammatory Bowel Disease II: Ulcerative Colitis
