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A fatal case of severe methaemoglobinemia due to nitrobenzene poisoning
Alok Gupta1, Nirdesh Jain, Avinash Agrawal
1Department of Internal Medicine, CSM Medical University, Lucknow, Uttar Pradesh, India.
Abstract:
An acute poisoning with nitrobenzene presenting as methaemoglobinemia is an uncommon medical emergency. A young girl with nitrobenzene induced methaemoglobinaemia died despite use of mechanical ventilator, administration of oral methylene blue and parenteral ascorbic acid. Here author highlights the rare occurrence of such cases, methaemoglobin induced severe oxidative stress, unexplained splenomegaly and leucocytosis and the ineffectivity of oral methylene blue and other supportive measures in evading death due to nitrobenzene poisoning.
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